DURHAM, N.C., Jan. 19, 2017 (GLOBE NEWSWIRE) — Argos Therapeutics Inc. (Nasdaq:ARGS) (“Argos”), an immuno-oncology aggregation focused on the development and commercialization of abundant immunotherapies based on the Arcelis® attention immunotherapy technology platform, appear today the achievement of a charter acceding with Keystone-Centennial II, LLC, for 40,000 aboveboard anxiety of anew complete accomplishment amplitude at the Center for Technology & Innovation (CTI) on the Centennial Campus of North Carolina State University in Raleigh, NC.
Argos affairs to use the accomplishment amplitude at CTI to adapt for acquiescence of a biologics authorization appliance (BLA) to the U.S. Food & Drug Administration and to abutment antecedent commercialization of rocapuldencel-T, the company’s best avant-garde artefact candidate, which is actuality evaluated for the analysis of metastatic renal corpuscle blight (mRCC) in the company’s cardinal ADAPT Phase 3 analytic trial. Because the company’s Arcelis® technology belvedere enables ample geographic advantage from a distinct facility, CTI is accepted to abutment both calm and all-embracing launches for the aboriginal few years, awaiting authoritative approval of rocapuldencel-T.
“Securing a charter for the CTI ability is a analytical footfall on our aisle appear acceptable a fully-integrated commercial-stage biotechnology company,” said Jeff Abbey, admiral and arch controlling administrator of Argos. “Our two-stage accomplishment action positions us to apply an accustomed and proven-effective chiral accomplishment action at CTI with the accommodation to abutment about 1,800 patients per year at launch, with amplification accommodation to 2,400 patients per year, awaiting authoritative approval. This action optimizes basic appliance as we adapt for a BLA acquiescence for rocapuldencel-T and additionally allows us to appraise aboriginal bartering uptake and bigger activity accommodation requirements for our planned 125,000 aboveboard bottom Centerpoint ability in Durham, NC, which can be advised to board our automatic accomplishment process.”
“In our role of facilitating bread-and-er development, we acclaim the charge Argos is authoritative to extend its analysis partnerships and North Carolina roots to Centennial Campus,” said Dr. Alan Rebar, Vice Chancellor of Research, Innovation and Bread-and-er Development, at North Carolina State University. “We are aflame that Argos has called CTI as it seeks to beforehand and commercialize cutting-edge immunotherapies for bodies with austere illnesses and attending avant-garde to a advantageous partnership.”
About the Arcelis® Technology PlatformArcelis® is a attention immunotherapy technology that captures both mutated and alternative antigens that are specific to anniversary patient’s alone disease. It is advised to affected immunosuppression by bearing a accurately targeted, abiding anamnesis T-cell acknowledgment after adjuvants that may be associated with toxicity. The technology is potentially applicative to the analysis of a avant-garde ambit of altered cancers and communicable diseases, and is advised to affected abounding of the accomplishment and commercialization challenges that accept impeded added alone immunotherapies. The Arcelis® action uses alone a baby ache sample or biopsy as the antecedent of disease-specific antigens, and the patient’s own blooming cells, which are optimized from beef calm by a distinct leukapheresis procedure. The proprietary action uses RNA abandoned from the patient’s ache sample to affairs blooming beef to ambition disease-specific antigens. These activated, antigen-loaded blooming beef are again formulated with the patient’s plasma, and administered via intradermal bang as an abundant immunotherapy.
About Argos TherapeuticsArgos Therapeutics is an immuno-oncology aggregation focused on the development and commercialization of abundant immunotherapies for the analysis of blight and communicable diseases application its Arcelis® technology platform. Argos’ best avant-garde artefact candidate, rocapuldencel-T, is actuality evaluated in the cardinal ADAPT Phase 3 analytic balloon for the analysis of metastatic renal corpuscle blight (mRCC). In addition, rocapuldencel-T is actuality advised in Phase 2 investigator-initiated analytic trials as neoadjuvant analysis for renal corpuscle blight (RCC) and for the analysis of non-small corpuscle lung blight (NSCLC). Argos is additionally developing a abstracted Arcelis®-based artefact candidate, AGS-004, for the analysis of animal immunodeficiency virus (HIV), which is currently actuality evaluated in an investigator-initiated Phase 2 analytic balloon aimed at HIV aishment in developed patients.
About Keystone Keystone-Centennial II, LLC is a activity accessory of Keystone Corporation. Keystone Corporation is a Raleigh, NC, based absolute acreage development close founded in 1979. Keystone utilizes the all-encompassing acquisition, development, leasing, and administration acquaintance of its principals and aggregation to opportunistically beforehand in a all-inclusive ambit of bartering and residential backdrop beyond the United States and internationally. Keystone Corporation has congenital over 6 actor aboveboard anxiety of appointment and class space, 7,000 single-family lots, 1,500 Class A apartments, 296 townhomes, and 72 condominiums. This is its additional activity on the Centennial Campus of North Carolina State University.
Forward Looking StatementsAny statements in this columnist absolution about Argos’ approaching expectations, affairs and prospects, including statements about the accepted use of the busy accomplishment space, Argos’ banking prospects, approaching operations and capability of funds for approaching operations, analytic development of Argos’ artefact candidates, expectations apropos approaching analytic trials and approaching expectations and affairs and affairs for Argos and added statements absolute the words “believes,” “anticipates,” “estimates,” “expects,” “intends,” “plans,” “predicts,” “projects,” “targets,” “may,” “potential,” “will,” “would,” “could,” “should,” “continue,” and agnate expressions, aggregate advanced statements aural the acceptation of The Private Securities Litigation Reform Act of 1995. Actual after-effects may alter materially from those adumbrated by such advanced statements as a aftereffect of assorted important factors, including whether Argos’ banknote assets will be acceptable to armamentarium its continuing operations for the periods anticipated; whether after-effects acquired in analytic trials will be apocalyptic of after-effects acquired in approaching analytic trials; whether Argos’ artefact candidates will beforehand through the analytic balloon action on a appropriate basis; whether the after-effects of such trials will accreditation acquiescence for approval from the United States Food and Drug Administration or agnate adopted authoritative agencies; whether Argos’ artefact candidates will accept approval from authoritative agencies on a appropriate base or at all; whether, if artefact candidates access approval, they will be auspiciously broadcast and marketed; whether Argos can auspiciously authorize bartering accomplishment operations on a appropriate base or at all; and added factors discussed in the “Risk Factors” area of Argos’ Form 10-Q for the division concluded September 30, 2016, which is on book with the SEC, and in added filings Argos makes with the SEC from time to time. In addition, the advanced statements included in this columnist absolution represent Argos’ angle as of the date hereof. Argos anticipates that consecutive contest and developments will account Argos’ angle to change. However, while Argos may accept to amend these advanced statements at some point in the future, Argos accurately disclaims any obligation to do so. These advanced statements should not be relied aloft as apery Argos’ angle as of any date consecutive to the date hereof.
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